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Leukocyte adhesion and neutrophil infiltration decline in affected tissues[7]
Several factors influence how noticeable skin laxity becomes: Loss of fat that once helped fill out the skin Natural declines in collagen and elastin with age Genetics and baseline skin quality How much weight is lost and how quickly Areas like the abdomen, arms, thighs, neck, and lower face are especially prone to laxity because they rely heavily on structural support rather than muscle tone alone
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